STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
atpIATP synthase, subunit I; Produces ATP from ADP in the presence of a proton gradient across the membrane; Belongs to the V-ATPase 116 kDa subunit family. (658 aa)    
Predicted Functional Partners:
atpD
ATP synthase, subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane.
 
 0.999
atpB
ATP synthase, subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.
 
 0.999
atpA
ATP synthase, subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit (By similarity); Belongs to the ATPase alpha/beta chains family.
 
 0.999
atpF
ATP synthase, subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane.
 
 0.999
atpC
ATP synthase, subunit C; Produces ATP from ADP in the presence of a proton gradient across the membrane.
 
 0.999
atpE
ATP synthase, subunit E; Produces ATP from ADP in the presence of a proton gradient across the membrane.
 
 0.999
MTH_959
ATP synthase, subunit K; Function Code:2.01 - Energy Metabolism, Oxidative phosphorylation; similar to, sp:LN:ATPL_METJA AC:Q57674, p()=4E-19, pid=68%; Belongs to the V-ATPase proteolipid subunit family.
 
 0.999
MTH_961
Unknown; Function Code:14.00 - Unknown; similar to, sp:LN:Y223_METJA AC:Q57676, p()=0.0012, pid=46%.
  
 0.999
ppa
Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
   
 
 0.923
mtrC
N5-methyl-tetrahydromethanopterin:coenzyme M methyltransferase, subunit C; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
    
   0.846
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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