Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-expression
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[Homology]
Score
MTH_975Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:I41284 AC:I41284, p()=0.017, pid=15%. (246 aa)    
Predicted Functional Partners:
MTH_679
Unknown; Function Code:14.00 - Unknown; similar to, sp:LN:SECD_MYCTU, p()=0.97, pid=%.
       0.643
MTH_974
Unknown; Function Code:14.00 - Unknown; similar to, pir:LN:E64439 AC:E64439, p()=0.0012, pid=18%.
       0.557
nadX
Conserved protein; Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
       0.547
MTH_972
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:YG1G_YEAST AC:P53215, p()=6.7E-09, pid=21%.
       0.546
MTH_677
Unknown; Function Code:14.00 - Unknown; similar to, pir:LN:G64514 AC:G64514, p()=0.14, pid=25%; Belongs to the UPF0440 family.
       0.513
MTH_971
Unknown; Function Code:14.00 - Unknown; similar to, gp:GI:g1469185 LN:D50921, p()=0.85, pid=15%.
       0.428
MTH_680
Conserved protein; Probably involved in the biogenesis of the ribosome.
       0.418
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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