STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_978NADP-dependent glyceraldehyde-3-phosphate dehydrogenase; Function Code:1.01 - Carbohydrate Metabolism, Glycolysis--Gluconeogenesis; similar to, pir:LN:B64476 AC:B64476, p()=7.5E-77, pid=37%; Belongs to the aldehyde dehydrogenase family. (455 aa)    
Predicted Functional Partners:
MTH_984
1,3-propanediol dehydrogenase; Function Code:13.07 - Other, Unclassified; similar to, sp:LN:YIAY_ECOLI AC:P37686, p()=4.5E-70, pid=42%.
 
 
 0.972
MTH_1856
Sodium/proline symporter (proline permease); Function Code:12.01 - Cell Processes, Transport of amino acids--peptides and amines; similar to, sp:LN:PANF_HAEIN AC:P44963, p()=6.9E-27, pid=29%; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  
  
 0.905
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
  
 
 0.849
MTH_1639
Cell division control protein Cdc48; Function Code:12.07 - Cell Processes, Cell division; similar to, pir:LN:C64444 AC:C64444, p()=7.7E-233, pid=83%.
   
 0.842
MTH_105
Glutamate synthase (NADPH), alpha subunit; Function Code:5.01 - L-Amino Acid Metabolism, Alanine--aspartate and glutamate metabolism; similar to, pir:LN:F64468 AC:F64468, p()=7E-77, pid=33%; Belongs to the glutamate synthase family.
  
  
 0.840
MTH_476
Pyruvate dehydrogenase / acetolactate synthase; Function Code:1.08 - Carbohydrate Metabolism, Pyruvate and acetyl-CoA metabolism; similar to, gp:GI:g1881244 LN:AB001488, p()=1.8E-84, pid=32%; Belongs to the TPP enzyme family.
 
 0.835
MTH_1528
Coenzyme F390 synthetase I; Function Code:9.15 - Metabolism of Cofactors and Vitamins, Other cofactors; similar to, gp:GI:g1050923, p()=3.7E-194, pid=75%.
  
 
 0.827
MTH_161
Coenzyme F390 synthetase III; Function Code:9.15 - Metabolism of Cofactors and Vitamins, Other cofactors; similar to, gp:GI:g1787664 LN:ECAE000236, p()=5.6E-95, pid=43%.
  
 
 0.827
MTH_1855
Coenzyme F390 synthetase II; Function Code:9.15 - Metabolism of Cofactors and Vitamins, Other cofactors; similar to, gp:GI:g1787664 LN:ECAE000236, p()=7E-113, pid=49%.
  
 
 0.827
MTH_657
long-chain-fatty-acid-CoA ligase; Function Code:3.01 - Lipid Metabolism, Fatty acid biosynthesis; similar to, gp:GI:e276127:g1627854, p()=3.2E-101, pid=37%.
  
 
 0.804
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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