STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_995Lysyl endopeptidase; Function Code:10.12 - Metabolism of Macromolecules, Degradation of proteins--peptides--and glycopeptides; similar to, sp:LN:API_ACHLY AC:P15636, p()=1.5E-11, pid=13%. (445 aa)    
Predicted Functional Partners:
MTH_984
1,3-propanediol dehydrogenase; Function Code:13.07 - Other, Unclassified; similar to, sp:LN:YIAY_ECOLI AC:P37686, p()=4.5E-70, pid=42%.
  
    0.608
carB
Carbamoyl-phosphate synthase, large subunit; Function Code:5.01 - L-Amino Acid Metabolism, Alanine--aspartate and glutamate metabolism; similar to, gp:GI:g1750387 LN:PAU81259, p()=3.6E-219, pid=70%.
       0.601
MTH_997
Carbamoyl-phosphate synthase, large subunit; Function Code:5.01 - L-Amino Acid Metabolism, Alanine--aspartate and glutamate metabolism; similar to, pir:LN:A64472 AC:A64472, p()=2E-74, pid=58%.
       0.601
MTH_994
N-ethylammeline chlorohydrolase related protein; Function Code:13.07 - Other, Unclassified; similar to, pir:LN:C64387 AC:C64387, p()=1.3E-49, pid=35%; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
 
     0.583
MTH_993
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:C64366 AC:C64366, p()=4.6E-29, pid=46%.
  
    0.569
MTH_87
Surface protease related protein; Function Code:10.12 - Metabolism of Macromolecules, Degradation of proteins--peptides--and glycopeptides; similar to, gp:GI:e139488:g1213023, p()=5.5E-09, pid=38%.
 
     0.565
MTH_75
Surface protease related protein; Function Code:10.12 - Metabolism of Macromolecules, Degradation of proteins--peptides--and glycopeptides; similar to, gp:GI:e139488:g1213023, p()=5.7E-09, pid=39%.
 
     0.555
MTH_999
N-terminal acetyltransferase complex, subunit ARD1; Function Code:10.08 - Metabolism of Macromolecules, Protein translation and modification; similar to, pir:LN:A64491 AC:A64491, p()=3.5E-24, pid=38%.
  
    0.554
MTH_133
Cobalt transport ATP-binding protein O; Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system (By similarity).
 
    0.548
ecfA
Cobalt transport ATP-binding protein O; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
 
    0.532
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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