STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
carBCarbamoyl-phosphate synthase, large subunit; Function Code:5.01 - L-Amino Acid Metabolism, Alanine--aspartate and glutamate metabolism; similar to, gp:GI:g1750387 LN:PAU81259, p()=3.6E-219, pid=70%. (828 aa)    
Predicted Functional Partners:
carA
Carbamoyl-phosphate synthase, small subunit; Function Code:5.01 - L-Amino Acid Metabolism, Alanine--aspartate and glutamate metabolism; similar to, pir:LN:B64427 AC:B64427, p()=1.1E-100, pid=51%; Belongs to the CarA family.
 0.999
pyrB
Aspartate carbamoyltransferase; Function Code:4.02 - Nucleotide Metabolism, Pyrimidine metabolism; similar to, pir:LN:D64497 AC:D64497, p()=3.7E-91, pid=54%.
 
 0.998
argF
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
 
 
 0.990
argG
Argininosuccinate synthase; Function Code:5.01 - L-Amino Acid Metabolism, Alanine--aspartate and glutamate metabolism; similar to, sp:LN:ASSY_METJA AC:Q60174, p()=2.4E-135, pid=62%; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
 
 
 0.989
pyrC
Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
 
 0.984
MTH_997
Carbamoyl-phosphate synthase, large subunit; Function Code:5.01 - L-Amino Acid Metabolism, Alanine--aspartate and glutamate metabolism; similar to, pir:LN:A64472 AC:A64472, p()=2E-74, pid=58%.
 
  
 
0.977
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
  
 
 0.966
pyrI
Aspartate carbamoyltransferase regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase.
  
 
  0.959
glmS
Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
   
 0.931
glnA
Glutamine synthetase; Probably involved in nitrogen metabolism via ammonium assimilation. Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
  
 
 0.930
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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