STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APR66580.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (126 aa)    
Predicted Functional Partners:
APR68095.1
Transcriptional regulator Crp; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.759
topC
DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...]
  
     0.561
APR66117.1
Paraquat-inducible membrane protein A; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.531
rnt
Ribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.
       0.515
pyrC
Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
       0.496
APR68765.1
Metal-dependent hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.466
APR65896.1
Elongation factor P-like protein YeiP; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the elongation factor P family.
  
     0.436
APR67328.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.429
APR66065.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.414
APR67800.1
DUF1289 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.414
Your Current Organism:
Thalassolituus oleivorans
NCBI taxonomy Id: 187493
Other names: DSM 14913, LMG 21420, LMG:21420, T. oleivorans, Thalassolituus oleivorans Yakimov et al. 2004, strain MIL-1
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