STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ODS42145.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (229 aa)    
Predicted Functional Partners:
ODS42143.1
rRNA metabolism protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.863
dphB
Diphthine synthase; S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis.
  
 0.812
ODS42144.1
Bifunctional hexulose-6-phosphate synthase/ribonuclease regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.773
ODS42548.1
Adenine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    0.715
ODS42128.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
     0.623
ODS41826.1
GTP-binding protein TypA; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.592
fusA
Elongation factor EF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
    
 0.592
ODS42854.1
GTP-binding protein TypA; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.592
ODS42142.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.580
eif2b
Translation initiation factor IF-2 subunit beta; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family.
  
     0.573
Your Current Organism:
Altiarchaeales archaeon
NCBI taxonomy Id: 1878999
Other names: C. Altiarchaeales archaeon IMC4, Candidatus Altiarchaeales archaeon IMC4
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.