STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrCHypothetical protein; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (434 aa)    
Predicted Functional Partners:
pyrB
Aspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.999
ODS42451.1
Carbamoyl-phosphate synthase large chain; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
carA
Carbamoyl phosphate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family.
 
 
 0.999
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 
 0.997
pyrD
Dihydroorotate dehydrogenase B catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate.
  
 0.994
MSIBF_06610
Hypothetical protein; Incomplete; too short partial abutting assembly gap; missing stop; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
 
 0.985
ODS42290.1
Dihydroorotate dehydrogenase electron transfer subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.969
pyrI
Aspartate carbamoyltransferase regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase.
    
 0.776
ODS41953.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.765
ODS42358.1
DNA-directed RNA polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.697
Your Current Organism:
Altiarchaeales archaeon
NCBI taxonomy Id: 1878999
Other names: C. Altiarchaeales archaeon IMC4, Candidatus Altiarchaeales archaeon IMC4
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.