STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hldEBifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. (455 aa)    
Predicted Functional Partners:
OTE96041.1
Phosphoheptose isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.997
OTE97168.1
Phosphoheptose isomerase; Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.991
hldD
ADP-glyceromanno-heptose 6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
 
 
  0.987
OTE96019.1
D-glycero-beta-D-manno-heptose-1,7-bisphosphate 7-phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.974
OTE95144.1
Lipopolysaccharide heptosyltransferase II; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.874
OTE95751.1
Putative lipopolysaccharide heptosyltransferase III; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.854
OTE95308.1
Lipopolysaccharide heptosyltransferase I; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.848
kdsA
3-deoxy-8-phosphooctulonate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the KdsA family.
    
 0.709
kdsB
3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
    
 0.686
murF
UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
   
 
  0.575
Your Current Organism:
Crenothrix sp. D3
NCBI taxonomy Id: 1880899
Other names: C. sp. D3
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.