STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHI47068.1Hypothetical protein. (259 aa)    
Predicted Functional Partners:
SHI16897.1
Diaminohydroxyphosphoribosylaminopyrimidine deaminase.
    
 0.803
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
    
  0.761
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.744
SHI38305.1
IMP dehydrogenase.
    
 0.689
SHH77388.1
DNA-3-methyladenine glycosylase II.
    
  0.673
SHH81253.1
DNA-3-methyladenine glycosylase II.
    
  0.673
SHI41071.1
Mannose-1-phosphate guanylyltransferase / phosphomannomutase.
  
 
 0.632
fbiB
Coenzyme F420-0 gamma-glutamyl ligase; Bifunctional enzyme that catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives, and the FMNH2- dependent reduction of dehydro-F420-0 to form F420-0.
    
  0.613
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
    
  0.610
SHI26537.1
Alpha-1,6-glucosidases, pullulanase-type.
    
  0.592
Your Current Organism:
Streptomyces sp. 32146
NCBI taxonomy Id: 1882757
Other names: S. sp. 3214.6, Streptomyces sp. 3214.6
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.