node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDM06053.1 | SDN26103.1 | SAMN05443253_101649 | SAMN05443253_109214 | Drug resistance transporter, EmrB/QacA subfamily; Belongs to the major facilitator superfamily. | Broad specificity phosphatase PhoE; Belongs to the phosphoglycerate mutase family. | 0.573 |
SDM06053.1 | gpmI | SAMN05443253_101649 | SAMN05443253_105147 | Drug resistance transporter, EmrB/QacA subfamily; Belongs to the major facilitator superfamily. | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the BPG-independent phosphoglycerate mutase family. | 0.769 |
SDM78886.1 | SDN01695.1 | SAMN05443253_105317 | SAMN05443253_107165 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Fructose-bisphosphate aldolase. | 0.446 |
SDM78886.1 | SDN26103.1 | SAMN05443253_105317 | SAMN05443253_109214 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Broad specificity phosphatase PhoE; Belongs to the phosphoglycerate mutase family. | 0.714 |
SDM78886.1 | eno | SAMN05443253_105317 | SAMN05443253_105148 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.566 |
SDM78886.1 | glyA | SAMN05443253_105317 | SAMN05443253_107184 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.973 |
SDM78886.1 | gpmI | SAMN05443253_105317 | SAMN05443253_105147 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the BPG-independent phosphoglycerate mutase family. | 0.736 |
SDM78886.1 | pfkA | SAMN05443253_105317 | SAMN05443253_102500 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.493 |
SDM78886.1 | serC | SAMN05443253_105317 | SAMN05443253_101425 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Phosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | 0.985 |
SDN00656.1 | SDN26103.1 | SAMN05443253_107127 | SAMN05443253_109214 | Molybdopterin molybdochelatase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | Broad specificity phosphatase PhoE; Belongs to the phosphoglycerate mutase family. | 0.663 |
SDN01695.1 | SDM78886.1 | SAMN05443253_107165 | SAMN05443253_105317 | Fructose-bisphosphate aldolase. | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.446 |
SDN01695.1 | SDN26103.1 | SAMN05443253_107165 | SAMN05443253_109214 | Fructose-bisphosphate aldolase. | Broad specificity phosphatase PhoE; Belongs to the phosphoglycerate mutase family. | 0.571 |
SDN01695.1 | eno | SAMN05443253_107165 | SAMN05443253_105148 | Fructose-bisphosphate aldolase. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.973 |
SDN01695.1 | glyA | SAMN05443253_107165 | SAMN05443253_107184 | Fructose-bisphosphate aldolase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.487 |
SDN01695.1 | gpmI | SAMN05443253_107165 | SAMN05443253_105147 | Fructose-bisphosphate aldolase. | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the BPG-independent phosphoglycerate mutase family. | 0.828 |
SDN01695.1 | pfkA | SAMN05443253_107165 | SAMN05443253_102500 | Fructose-bisphosphate aldolase. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.901 |
SDN01695.1 | pgk | SAMN05443253_107165 | SAMN05443253_105145 | Fructose-bisphosphate aldolase. | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. | 0.988 |
SDN26103.1 | SDM06053.1 | SAMN05443253_109214 | SAMN05443253_101649 | Broad specificity phosphatase PhoE; Belongs to the phosphoglycerate mutase family. | Drug resistance transporter, EmrB/QacA subfamily; Belongs to the major facilitator superfamily. | 0.573 |
SDN26103.1 | SDM78886.1 | SAMN05443253_109214 | SAMN05443253_105317 | Broad specificity phosphatase PhoE; Belongs to the phosphoglycerate mutase family. | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.714 |
SDN26103.1 | SDN00656.1 | SAMN05443253_109214 | SAMN05443253_107127 | Broad specificity phosphatase PhoE; Belongs to the phosphoglycerate mutase family. | Molybdopterin molybdochelatase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | 0.663 |