node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDD94963.1 | SDE15325.1 | SAMN05444679_115131 | SAMN05444679_1189 | XTP/dITP diphosphohydrolase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Magnesium and cobalt transporter. | 0.497 |
SDD94963.1 | purA | SAMN05444679_115131 | SAMN05444679_111119 | XTP/dITP diphosphohydrolase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.870 |
SDD94963.1 | purH | SAMN05444679_115131 | SAMN05444679_118122 | XTP/dITP diphosphohydrolase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | IMP cyclohydrolase. | 0.606 |
SDD94963.1 | truA | SAMN05444679_115131 | SAMN05444679_108154 | XTP/dITP diphosphohydrolase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | tRNA pseudouridine38-40 synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.552 |
SDE15303.1 | SDE15325.1 | SAMN05444679_1188 | SAMN05444679_1189 | Protein N-acetyltransferase, RimJ/RimL family. | Magnesium and cobalt transporter. | 0.653 |
SDE15303.1 | lnt | SAMN05444679_1188 | SAMN05444679_11810 | Protein N-acetyltransferase, RimJ/RimL family. | Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. | 0.681 |
SDE15325.1 | SDD94963.1 | SAMN05444679_1189 | SAMN05444679_115131 | Magnesium and cobalt transporter. | XTP/dITP diphosphohydrolase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.497 |
SDE15325.1 | SDE15303.1 | SAMN05444679_1189 | SAMN05444679_1188 | Magnesium and cobalt transporter. | Protein N-acetyltransferase, RimJ/RimL family. | 0.653 |
SDE15325.1 | SDE15744.1 | SAMN05444679_1189 | SAMN05444679_11825 | Magnesium and cobalt transporter. | D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase. | 0.480 |
SDE15325.1 | glyQ | SAMN05444679_1189 | SAMN05444679_11823 | Magnesium and cobalt transporter. | glycyl-tRNA synthetase alpha chain. | 0.416 |
SDE15325.1 | glyS | SAMN05444679_1189 | SAMN05444679_11824 | Magnesium and cobalt transporter. | glycyl-tRNA synthetase beta chain. | 0.416 |
SDE15325.1 | lnt | SAMN05444679_1189 | SAMN05444679_11810 | Magnesium and cobalt transporter. | Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. | 0.934 |
SDE15325.1 | purA | SAMN05444679_1189 | SAMN05444679_111119 | Magnesium and cobalt transporter. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.513 |
SDE15325.1 | purH | SAMN05444679_1189 | SAMN05444679_118122 | Magnesium and cobalt transporter. | IMP cyclohydrolase. | 0.441 |
SDE15325.1 | truA | SAMN05444679_1189 | SAMN05444679_108154 | Magnesium and cobalt transporter. | tRNA pseudouridine38-40 synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.584 |
SDE15325.1 | ybeY | SAMN05444679_1189 | SAMN05444679_11892 | Magnesium and cobalt transporter. | Probable rRNA maturation factor; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.860 |
SDE15744.1 | SDE15325.1 | SAMN05444679_11825 | SAMN05444679_1189 | D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase. | Magnesium and cobalt transporter. | 0.480 |
SDE15744.1 | glyQ | SAMN05444679_11825 | SAMN05444679_11823 | D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase. | glycyl-tRNA synthetase alpha chain. | 0.852 |
SDE15744.1 | glyS | SAMN05444679_11825 | SAMN05444679_11824 | D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase. | glycyl-tRNA synthetase beta chain. | 0.856 |
SDE15744.1 | lnt | SAMN05444679_11825 | SAMN05444679_11810 | D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase. | Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. | 0.430 |