STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadKNAD+ kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (297 aa)    
Predicted Functional Partners:
nadE
NAD+ synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
    
 0.965
SFN57235.1
NAD(P) transhydrogenase subunit alpha.
     
 0.938
SFN57219.1
NAD(P) transhydrogenase subunit alpha.
     
 0.936
SFM89067.1
DNA repair protein RecN (Recombination protein N); May be involved in recombinational repair of damaged DNA.
 
  
 0.908
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
 
 0.890
SFM86002.1
Nudix N-terminal.
     
 0.832
SFM89088.1
UPF0042 nucleotide-binding protein; Displays ATPase and GTPase activities.
  
    0.812
SFM58632.1
Signal transduction histidine kinase.
    
  0.803
SFM20659.1
Two-component system, chemotaxis family, CheB/CheR fusion protein; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
    
  0.801
SFN50382.1
PAS domain S-box-containing protein.
    
  0.779
Your Current Organism:
Variovorax sp. OV329
NCBI taxonomy Id: 1882825
Other names: V. sp. OV329
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.