STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PDE5APhosphodiesterase. (822 aa)    
Predicted Functional Partners:
GMPR
GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
    
 0.909
GUK1
Guanylate kinase.
   
 
 0.904
ITPA
Inosine triphosphate pyrophosphatase.
     
 0.901
GMPS
GMP synthase [glutamine-hydrolyzing].
     
  0.900
GUCY1B3
Guanylate cyclase soluble subunit beta-1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
   
 0.853
GUCY2C
Guanylate cyclase.
   
 0.766
GUCY1A3
Guanylate cyclase soluble subunit alpha-3; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
   
 0.755
GUCY2F
Guanylate cyclase.
   
 0.751
CANT1
Soluble calcium-activated nucleotidase 1.
     
 0.749
NPR2
Atrial natriuretic peptide receptor 2.
   
 0.749
Your Current Organism:
Egretta garzetta
NCBI taxonomy Id: 188379
Other names: E. garzetta, little egret
Server load: low (24%) [HD]