STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IGF1RTyrosine-protein kinase receptor. (1153 aa)    
Predicted Functional Partners:
Z169_10591
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
    
 0.981
IGF1
Insulin-like growth factor I.
    
 0.977
IRS1
Insulin receptor substrate 1.
   
 0.973
GRB2
Growth factor receptor-bound protein 2.
   
 0.949
CTNNB1
Catenin beta-1.
   
 0.925
PTK2
Focal adhesion kinase 1.
    
0.924
PRKACB
cAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily.
   
0.911
EPS15L1
Epidermal growth factor receptor substrate 15-like 1.
    
  0.907
EPS15
Epidermal growth factor receptor substrate 15.
    
  0.907
EPN2
Epsin-2.
    
  0.901
Your Current Organism:
Egretta garzetta
NCBI taxonomy Id: 188379
Other names: E. garzetta, little egret
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.