STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Z169_14868Histone H2A; Belongs to the histone H2A family. (104 aa)    
Predicted Functional Partners:
Z169_15445
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
 
 
 0.996
EP400
E1A-binding protein p400.
    
 0.990
ARID4A
AT-rich interactive domain-containing protein 4A.
   
 0.981
RUVBL1
RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.
   
 0.957
YEATS4
YEATS domain-containing protein 4.
   
 
 0.937
KDM6A
Lysine-specific demethylase 6A.
   
 0.937
ASF1A
Histone chaperone ASF1.
 
 
 
 0.934
Z169_07841
Primary ciliary dyskinesia protein 1.
    
 
 0.932
DMAP1
DNA methyltransferase 1-associated protein 1.
    
 
 0.921
ACTR6
Actin-related protein 6; Belongs to the actin family.
   
 
 0.911
Your Current Organism:
Egretta garzetta
NCBI taxonomy Id: 188379
Other names: E. garzetta, little egret
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.