STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Z169_11470Inducible T-cell costimulator. (212 aa)    
Predicted Functional Partners:
Z169_00713
ICOS ligand.
   
 0.962
CD86
T-lymphocyte activation antigen CD86.
  
  
 0.825
Z169_11471
Cytotoxic T-lymphocyte protein 4.
   
  
0.821
CD40LG
CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.
  
  
 0.808
CD80
T-lymphocyte activation antigen CD80.
  
 
 0.788
IFNG
Interferon gamma.
  
  
 0.727
IL7R
Interleukin-7 receptor subunit alpha.
  
  
 0.724
CD4
T-cell surface glycoprotein CD4.
  
  
 0.712
Z169_08110
Programmed cell death protein 1.
  
  
 0.653
IL21R
Interleukin-21 receptor.
  
  
 0.651
Your Current Organism:
Egretta garzetta
NCBI taxonomy Id: 188379
Other names: E. garzetta, little egret
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