STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TSEN54tRNA-splicing endonuclease subunit Sen54. (453 aa)    
Predicted Functional Partners:
TSEN2
tRNA-splicing endonuclease subunit Sen2; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural [...]
    
 0.962
TSEN15
tRNA-splicing endonuclease subunit Sen15.
    
 0.899
RARS2
DALR_1 domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family.
      
 0.652
TRMT2B
tRNA (Uracil(54)-C(5))-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
   
    0.582
MRPL13
Uncharacterized protein.
      
 0.491
HMBS
Porphobilinogen deaminase.
      
 0.446
RARS
Arginine--tRNA ligase, cytoplasmic; Belongs to the class-I aminoacyl-tRNA synthetase family.
      
 0.445
INTS1
Integrator complex subunit 1.
      
 0.445
SEPSECS
O-phosphoseryl-tRNA(Sec) selenium transferase.
      
 0.420
FNIP2
Folliculin-interacting protein 2.
      
 0.403
Your Current Organism:
Egretta garzetta
NCBI taxonomy Id: 188379
Other names: E. garzetta, little egret
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