STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANKRD31Putative ankyrin repeat domain-containing protein 31. (741 aa)    
Predicted Functional Partners:
RBBP8
DNA endonuclease RBBP8.
    
 0.833
MRE11A
Double-strand break repair protein MRE11; Belongs to the MRE11/RAD32 family.
   
 0.738
NBN
Nibrin.
    
 0.721
BRIP1
Fanconi anemia group J protein.
    
 0.680
Z169_01217
Ankyrin repeat domain-containing protein 32.
    
 0.634
TOPBP1
DNA topoisomerase 2-binding protein 1-A.
    
 0.634
RAD50
DNA repair protein RAD50.
    
 0.632
RAD51
DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]
   
 0.632
BRCA2
Breast cancer type 2 susceptibility protein.
    
 0.629
BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1.
    
 0.622
Your Current Organism:
Egretta garzetta
NCBI taxonomy Id: 188379
Other names: E. garzetta, little egret
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