STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FANCD2Fanconi anemia group D2 protein. (1415 aa)    
Predicted Functional Partners:
FANCI
Fanconi anemia group I protein.
   
 0.998
FANCL
E3 ubiquitin-protein ligase FANCL.
    
 0.998
FANCC
Fanconi anemia group C protein homolog; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1.
    
 0.995
FAN1
Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.
    
 0.991
UBE2T
Ubiquitin-conjugating enzyme E2 T; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.991
FANCB
Fanconi anemia group B protein.
   
 0.991
BRCA2
Breast cancer type 2 susceptibility protein.
   
 0.986
Z169_08646
Fanconi anemia-associated protein of 24 kDa.
     
 0.985
FANCE
Fanconi anemia group E protein.
    
 0.985
USP1
Ubiquitin carboxyl-terminal hydrolase.
    
 0.971
Your Current Organism:
Egretta garzetta
NCBI taxonomy Id: 188379
Other names: E. garzetta, little egret
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