STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPDL1Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex; Belongs to the Spindly family. (606 aa)    
Predicted Functional Partners:
Z169_15059
Cell division cycle protein 20.
   
 
  0.641
Z169_12904
Fizzy-related protein.
   
 
  0.546
PLK2
Serine/threonine-protein kinase PLK2.
   
 
  0.538
PLK3
Serine/threonine-protein kinase PLK3.
   
 
  0.538
ECT2
Protein ECT2.
  
    0.500
INTU
Protein inturned.
   
 
  0.471
BUB1B
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta.
   
 
  0.425
CDC20B
Cell division cycle protein 20 B.
   
 
  0.421
MAD2L1
Mitotic spindle assembly checkpoint protein MAD2A.
   
 
  0.420
Your Current Organism:
Egretta garzetta
NCBI taxonomy Id: 188379
Other names: E. garzetta, little egret
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.