STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIM2Single-minded 2. (512 aa)    
Predicted Functional Partners:
HIF1A
Hypoxia-inducible factor 1-alpha.
 
    
 0.902
Z169_10548
Aryl hydrocarbon receptor nuclear translocator.
    
 
0.824
ARNT2
Aryl hydrocarbon receptor nuclear translocator 2.
    
 
0.824
ARNTL
Aryl hydrocarbon receptor nuclear translocator-like 1.
   
 
0.535
Z169_07779
Nuclear receptor coactivator 1.
    
 
0.530
Z169_11781
Neuronal PAS domain-containing protein 2.
    
 
0.530
TRH
Pro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.
      
 0.513
AGRP
Agouti-related protein.
      
 0.487
RHBDL3
Rhomboid-related protein 3; Belongs to the peptidase S54 family.
   
  
 0.452
PRRX2
Uncharacterized protein.
   
  
 0.451
Your Current Organism:
Egretta garzetta
NCBI taxonomy Id: 188379
Other names: E. garzetta, little egret
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.