LHFP protein (Egretta garzetta) - STRING interaction network

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second shell of interactors

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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[Homology]

Score

LHFP

Lipoma HMGIC fusion partner. (129 aa)

Predicted Functional Partners:

COG6

0.533

HTR2C

0.497

MRPS31

0.487

Z169_08776

0.413

Z169_09594

0.409

Your Current Organism:

Egretta garzetta

NCBI taxonomy Id: 188379
Other names: E. garzetta, little egret

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
COG6	LHFP	A0A091JGZ8	A0A091JDS5	Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.	Lipoma HMGIC fusion partner.	0.533
COG6	MRPS31	A0A091JGZ8	A0A091K5X9	Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.	Uncharacterized protein.	0.493
HTR2C	LHFP	A0A091IZG6	A0A091JDS5	5-hydroxytryptamine receptor 2C.	Lipoma HMGIC fusion partner.	0.497
LHFP	COG6	A0A091JDS5	A0A091JGZ8	Lipoma HMGIC fusion partner.	Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.	0.533
LHFP	HTR2C	A0A091JDS5	A0A091IZG6	Lipoma HMGIC fusion partner.	5-hydroxytryptamine receptor 2C.	0.497
LHFP	MRPS31	A0A091JDS5	A0A091K5X9	Lipoma HMGIC fusion partner.	Uncharacterized protein.	0.487
LHFP	Z169_08776	A0A091JDS5	A0A091ISD0	Lipoma HMGIC fusion partner.	Protein unc-79.	0.413
LHFP	Z169_09594	A0A091JDS5	A0A091JL76	Lipoma HMGIC fusion partner.	Phosphatase and actin regulator.	0.409
MRPS31	COG6	A0A091K5X9	A0A091JGZ8	Uncharacterized protein.	Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.	0.493
MRPS31	LHFP	A0A091K5X9	A0A091JDS5	Uncharacterized protein.	Lipoma HMGIC fusion partner.	0.487
Z169_08776	LHFP	A0A091ISD0	A0A091JDS5	Protein unc-79.	Lipoma HMGIC fusion partner.	0.413
Z169_09594	LHFP	A0A091JL76	A0A091JDS5	Phosphatase and actin regulator.	Lipoma HMGIC fusion partner.	0.409

Network Stats

number of nodes:

11

number of edges:

37

average node degree:

6.73

avg. local clustering coefficient:

0.793

expected number of edges:

39

PPI enrichment p-value:

0.658

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000160

Phosphorelay signal transduction system

6 of 122

1.26

1.16

0.00047

GO:0050794

Regulation of cellular process

8 of 568

0.72

0.54

0.0038

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0043565

Sequence-specific DNA binding

5 of 89

1.32

1.07

0.0018

GO:0052621

Diguanylate cyclase activity

3 of 19

1.77

1.04

0.0084

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:4528

Diguanylate cyclase activity, and Putative diguanylate phosphodiesterase

8 of 25

2.08

5.22

2.65e-13

CL:4530

Diguanylate cyclase activity, and Putative diguanylate phosphodiesterase

7 of 18

2.16

5.01

5.40e-12

CL:4521

Diguanylate cyclase, and HD-GYP domain

10 of 50

1.87

4.98

2.06e-15

CL:4531

Putative diguanylate phosphodiesterase, and Domain present in phytochromes and cGMP-specific phosphodiesterases.

6 of 13

2.24

4.57

1.95e-10

CL:4534

Mixed, incl. Double Cache domain 1, and CHASE domain

3 of 6

2.27

2.07

0.00011

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00267

Diguanylate cyclase

9 of 50

1.83

4.45

9.02e-14

SM00065

Domain present in phytochromes and cGMP-specific phosphodiesterases.

4 of 14

2.03

2.54

5.11e-06

SM00091

PAS domain

4 of 52

1.46

1.37

0.00039

SM00086

Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)

3 of 36

1.49

1.08

0.0038

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