STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Z169_11345Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (96 aa)    
Predicted Functional Partners:
FGFR2
Fibroblast growth factor receptor.
    
 0.760
EGF
Pro-epidermal growth factor.
    
 
 0.686
KDR
Vascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
   
 0.614
FGF10
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
     
0.597
FGFR3
Fibroblast growth factor receptor 3.
    
 0.571
FGFR4
Fibroblast growth factor receptor 4.
    
 0.563
FGFRL1
Fibroblast growth factor receptor-like 1.
    
 0.540
Z169_10591
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
   
  
 0.531
BDNF
Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family.
      
 0.512
HGF
Hepatocyte growth factor; Belongs to the peptidase S1 family.
      
 0.510
Your Current Organism:
Egretta garzetta
NCBI taxonomy Id: 188379
Other names: E. garzetta, little egret
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.