STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTHFD1C-1-tetrahydrofolate synthase, cytoplasmic. (921 aa)    
Predicted Functional Partners:
ATIC
Bifunctional purine biosynthesis protein PURH.
  
 0.995
SHMT1
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 0.995
FTCD
Formimidoyltransferase-cyclodeaminase.
    
 0.991
MTHFS
5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.
   
 0.986
MTHFD2
Uncharacterized protein.
  
 
0.986
MTHFD2L
Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2.
  
 
0.986
MTHFR
Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
  
 
 0.982
MTFMT
Uncharacterized protein.
    
 0.981
DHFR
Dihydrofolate reductase.
  
 
 0.979
TYMS
Thymidylate synthase.
  
 
 0.975
Your Current Organism:
Egretta garzetta
NCBI taxonomy Id: 188379
Other names: E. garzetta, little egret
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.