STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CBLE3 ubiquitin-protein ligase CBL. (853 aa)    
Predicted Functional Partners:
MET
Hepatocyte growth factor receptor.
   
 0.998
ERBB4
Receptor protein-tyrosine kinase.
    
 0.991
GRB2
Growth factor receptor-bound protein 2.
    
 0.990
SPRY2
Protein sprouty 2.
    
 0.982
CRK
Adapter molecule crk.
    
 0.959
CRKL
Crk-like.
    
 0.955
Z169_08494
Non-specific protein-tyrosine kinase.
    
 0.942
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.937
INSR
Tyrosine-protein kinase receptor.
    
 0.933
SMURF2
E3 ubiquitin-protein ligase SMURF2.
    
 0.928
Your Current Organism:
Egretta garzetta
NCBI taxonomy Id: 188379
Other names: E. garzetta, little egret
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.