STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Z169_14752Bromodomain testis-specific protein. (972 aa)    
Predicted Functional Partners:
Z169_15445
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 
 0.687
TAF7L
Transcription initiation factor TFIID subunit 7.
    
 
 0.651
DMAP1
DNA methyltransferase 1-associated protein 1.
    
 
 0.574
E2F1
Transcription factor E2F1.
    
 
 0.571
EP400
E1A-binding protein p400.
   
 
 0.537
Z169_14914
Histone-lysine N-methyltransferase NSD3.
   
 
 0.521
JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6.
    
 
 0.519
CDK9
Cyclin-dependent kinase 9.
   
 
 0.489
YEATS4
YEATS domain-containing protein 4.
    
 
 0.448
Z169_14868
Histone H2A; Belongs to the histone H2A family.
    
 
 0.447
Your Current Organism:
Egretta garzetta
NCBI taxonomy Id: 188379
Other names: E. garzetta, little egret
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