STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RFWD2E3 ubiquitin-protein ligase RFWD2. (580 aa)    
Predicted Functional Partners:
DET1
DET1.
    
 0.976
DDB2
DNA damage-binding protein 2.
    
 0.976
ERCC8
DNA excision repair protein ERCC-8.
    
  0.955
DDB1
DNA damage-binding protein 1.
    
 0.853
Z169_12074
RING-box protein 1.
    
 0.736
DDA1
DET1-and DDB1-associated protein 1.
    
  0.644
CUL4B
Cullin-4B; Belongs to the cullin family.
    
 0.643
CUL4A
Cullin-4A; Belongs to the cullin family.
    
 0.643
UBB
Polyubiquitin-C.
    
 0.618
RPS27A
Ubiquitin-40S ribosomal protein S27a.
    
  0.617
Your Current Organism:
Egretta garzetta
NCBI taxonomy Id: 188379
Other names: E. garzetta, little egret
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.