A0A5C3Q8D3 protein (Pterula gracilis) - STRING interaction network

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

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Score

A0A5C3Q8D3

TEA domain-containing protein. (492 aa)

Predicted Functional Partners:

A0A5C3QK64

0.871

A0A5C3QMS2

0.871

A0A5C3QPU3

0.871

A0A5C3QR52

0.871

A0A5C3QY57

0.871

A0A5C3Q2T1

0.643

A0A5C3QFC6

0.589

A0A5C3QFV0

0.589

A0A5C3QJ89

0.589

A0A5C3QLH5

0.589

Your Current Organism:

Pterula gracilis

NCBI taxonomy Id: 1884261
Other names: Hirsutella gracilis, P. gracilis, Pistillaria gracilis, Typhula gracilis

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A5C3Q2T1	A0A5C3Q8D3	HMG box domain-containing protein.	TEA domain-containing protein.	0.643
A0A5C3Q8D3	A0A5C3Q2T1	TEA domain-containing protein.	HMG box domain-containing protein.	0.643
A0A5C3Q8D3	A0A5C3QFC6	TEA domain-containing protein.	dUTP pyrophosphatase.	0.589
A0A5C3Q8D3	A0A5C3QFV0	TEA domain-containing protein.	Uncharacterized protein.	0.589
A0A5C3Q8D3	A0A5C3QJ89	TEA domain-containing protein.	Uncharacterized protein.	0.589
A0A5C3Q8D3	A0A5C3QK64	TEA domain-containing protein.	Cortical protein marker for cell polarity-domain-containing protein.	0.871
A0A5C3Q8D3	A0A5C3QLH5	TEA domain-containing protein.	Uncharacterized protein.	0.589
A0A5C3Q8D3	A0A5C3QMS2	TEA domain-containing protein.	Uncharacterized protein.	0.871
A0A5C3Q8D3	A0A5C3QPU3	TEA domain-containing protein.	Putative zinc-finger of transcription factor IIIC complex-domain-containing protein.	0.871
A0A5C3Q8D3	A0A5C3QR52	TEA domain-containing protein.	E3 ubiquitin-protein ligase.	0.871
A0A5C3Q8D3	A0A5C3QY57	TEA domain-containing protein.	E3 ubiquitin-protein ligase.	0.871
A0A5C3QFC6	A0A5C3Q8D3	dUTP pyrophosphatase.	TEA domain-containing protein.	0.589
A0A5C3QFV0	A0A5C3Q8D3	Uncharacterized protein.	TEA domain-containing protein.	0.589
A0A5C3QJ89	A0A5C3Q8D3	Uncharacterized protein.	TEA domain-containing protein.	0.589
A0A5C3QK64	A0A5C3Q8D3	Cortical protein marker for cell polarity-domain-containing protein.	TEA domain-containing protein.	0.871
A0A5C3QLH5	A0A5C3Q8D3	Uncharacterized protein.	TEA domain-containing protein.	0.589
A0A5C3QMS2	A0A5C3Q8D3	Uncharacterized protein.	TEA domain-containing protein.	0.871
A0A5C3QPU3	A0A5C3Q8D3	Putative zinc-finger of transcription factor IIIC complex-domain-containing protein.	TEA domain-containing protein.	0.871
A0A5C3QR52	A0A5C3Q8D3	E3 ubiquitin-protein ligase.	TEA domain-containing protein.	0.871
A0A5C3QR52	A0A5C3QY57	E3 ubiquitin-protein ligase.	E3 ubiquitin-protein ligase.	0.763

page 1 of 2

Network Stats

number of nodes:

11

number of edges:

31

average node degree:

5.64

avg. local clustering coefficient:

0.911

expected number of edges:

10

PPI enrichment p-value:

1.35e-07

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016114

Terpenoid biosynthetic process

8 of 12

2.42

6.7

7.87e-15

GO:0019288

Isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway

7 of 7

2.6

6.7

4.66e-14

GO:0090407

Organophosphate biosynthetic process

8 of 130

1.39

2.15

9.06e-09

GO:0019637

Organophosphate metabolic process

9 of 177

1.3

2.01

1.62e-09

GO:1901135

Carbohydrate derivative metabolic process

9 of 210

1.23

1.77

6.72e-09

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016725

Oxidoreductase activity, acting on CH or CH2 groups

3 of 8

2.17

1.51

0.0013

GO:0051745

4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity

2 of 2

2.6

1.13

0.0086

GO:0051539

4 iron, 4 sulfur cluster binding

3 of 29

1.61

0.99

0.0086

GO:0046872

Metal ion binding

7 of 488

0.75

0.52

0.0086

GO:0043167

Ion binding

9 of 894

0.6

0.43

0.0086

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005829

Cytosol

5 of 250

0.9

0.53

0.0261

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:4282

Isoprenoid biosynthetic process

7 of 11

2.4

5.82

8.50e-13

CL:4281

Isoprenoid metabolic process, and Carotenoid biosynthesis

8 of 21

2.18

5.54

2.10e-13

CL:4284

Isoprene biosynthesis

5 of 5

2.6

4.56

1.70e-09

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00900

Terpenoid backbone biosynthesis

8 of 18

2.24

6.19

1.03e-14

map01110

Biosynthesis of secondary metabolites

9 of 542

0.82

0.78

2.19e-05

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0414

Isoprene biosynthesis

8 of 8

2.6

7.82

1.38e-16

KW-0004

4Fe-4S

3 of 25

1.68

1.22

0.0026

KW-0479

Metal-binding

7 of 228

1.08

1.13

3.48e-05

KW-0560

Oxidoreductase

4 of 118

1.13

0.79

0.0069

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF02401

LytB protein

2 of 2

2.6

0.91

0.0220

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