A0A5C3QY46 protein (Pterula gracilis) - STRING interaction network

Nodes:

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second shell of interactors

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proteins of unknown 3D structure

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Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

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[Homology]

Score

A0A5C3QY46

Antiviral helicase. (1072 aa)

Predicted Functional Partners:

A0A5C3Q5C2

0.996

A0A5C3Q810

0.996

A0A5C3QUT3

0.993

A0A5C3QYG2

0.993

A0A5C3R2N6

0.993

A0A5C3QN45

0.991

A0A5C3Q4N6

0.989

A0A5C3R2J7

0.989

A0A5C3Q6B6

0.988

A0A5C3QGW0

0.988

Your Current Organism:

Pterula gracilis

NCBI taxonomy Id: 1884261
Other names: Hirsutella gracilis, P. gracilis, Pistillaria gracilis, Typhula gracilis

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A5C3Q4N6	A0A5C3Q5C2	Ribosomal protein S5 domain 2-like protein.	RNase_PH domain-containing protein.	0.999
A0A5C3Q4N6	A0A5C3Q6B6	Ribosomal protein S5 domain 2-like protein.	DUF663-domain-containing protein.	0.942
A0A5C3Q4N6	A0A5C3Q810	Ribosomal protein S5 domain 2-like protein.	Ribosomal protein S5 domain 2-type protein.	0.999
A0A5C3Q4N6	A0A5C3QGW0	Ribosomal protein S5 domain 2-like protein.	Utp14 protein-domain-containing protein.	0.938
A0A5C3Q4N6	A0A5C3QN45	Ribosomal protein S5 domain 2-like protein.	S1 domain-containing protein.	0.999
A0A5C3Q4N6	A0A5C3QUT3	Ribosomal protein S5 domain 2-like protein.	WD-repeat-containing protein.	0.891
A0A5C3Q4N6	A0A5C3QY46	Ribosomal protein S5 domain 2-like protein.	Antiviral helicase.	0.989
A0A5C3Q4N6	A0A5C3QYG2	Ribosomal protein S5 domain 2-like protein.	Uncharacterized protein.	0.903
A0A5C3Q4N6	A0A5C3R2J7	Ribosomal protein S5 domain 2-like protein.	Ribosomal protein S5 domain 2-type protein.	0.999
A0A5C3Q5C2	A0A5C3Q4N6	RNase_PH domain-containing protein.	Ribosomal protein S5 domain 2-like protein.	0.999
A0A5C3Q5C2	A0A5C3Q6B6	RNase_PH domain-containing protein.	DUF663-domain-containing protein.	0.941
A0A5C3Q5C2	A0A5C3Q810	RNase_PH domain-containing protein.	Ribosomal protein S5 domain 2-type protein.	0.998
A0A5C3Q5C2	A0A5C3QGW0	RNase_PH domain-containing protein.	Utp14 protein-domain-containing protein.	0.952
A0A5C3Q5C2	A0A5C3QN45	RNase_PH domain-containing protein.	S1 domain-containing protein.	0.999
A0A5C3Q5C2	A0A5C3QUT3	RNase_PH domain-containing protein.	WD-repeat-containing protein.	0.932
A0A5C3Q5C2	A0A5C3QY46	RNase_PH domain-containing protein.	Antiviral helicase.	0.996
A0A5C3Q5C2	A0A5C3QYG2	RNase_PH domain-containing protein.	Uncharacterized protein.	0.895
A0A5C3Q5C2	A0A5C3R2J7	RNase_PH domain-containing protein.	Ribosomal protein S5 domain 2-type protein.	0.999
A0A5C3Q6B6	A0A5C3Q4N6	DUF663-domain-containing protein.	Ribosomal protein S5 domain 2-like protein.	0.942
A0A5C3Q6B6	A0A5C3Q5C2	DUF663-domain-containing protein.	RNase_PH domain-containing protein.	0.941

page 1 of 6

Network Stats

number of nodes:

11

number of edges:

38

average node degree:

6.91

avg. local clustering coefficient:

0.895

expected number of edges:

36

PPI enrichment p-value:

0.415

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0051144

Propanediol catabolic process

3 of 6

2.21

1.42

0.0021

GO:0006066

Alcohol metabolic process

4 of 46

1.45

1.14

0.0021

GO:0044282

Small molecule catabolic process

4 of 114

1.06

0.6

0.0276

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016903

Oxidoreductase activity, acting on the aldehyde or oxo group of donors

4 of 15

1.94

1.91

0.00012

GO:0016620

Oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

3 of 11

1.95

1.33

0.0025

GO:0030976

Thiamine pyrophosphate binding

2 of 4

2.21

0.87

0.0245

GO:0016491

Oxidoreductase activity

5 of 232

0.85

0.46

0.0438

GO:0003824

Catalytic activity

11 of 1565

0.36

0.27

0.0245

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0031469

Bacterial microcompartment

4 of 40

1.51

1.33

0.00074

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:35494230

(2022) Bacteroides ovatus colonization influences the abundance of intestinal short chain fatty acids and neurotransmitters.

2 of 6

2.04

0.89

0.0216

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1463

Butanoate metabolism, and Propanoate metabolism

9 of 59

1.7

3.58

7.76e-12

CL:1465

Pyruvate metabolism, and Geraniol degradation

6 of 25

1.89

3.31

1.28e-08

CL:1469

Pyruvate ferredoxin/flavodoxin oxidoreductase, and Pyruvate:ferredoxin oxidoreductase core domain II

3 of 5

2.29

2.1

9.68e-05

CL:1557

Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA, and Aldehyde dehydrogenase family

3 of 12

1.91

1.58

0.00065

CL:1491

3-oxoacid CoA-transferase, and CoA carboxylase activity

3 of 12

1.91

1.58

0.00065

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

fpla00620

Pyruvate metabolism

9 of 50

1.77

4.13

2.46e-13

fpla00430

Taurine and hypotaurine metabolism

4 of 5

2.42

3.45

2.00e-07

fpla00650

Butanoate metabolism

5 of 39

1.62

2.21

1.80e-06

fpla00640

Propanoate metabolism

5 of 40

1.61

2.19

1.80e-06

fpla01120

Microbial metabolism in diverse environments

9 of 156

1.28

1.93

1.86e-09

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0031469

Polyhedral organelle

5 of 40

1.61

1.87

2.53e-05

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0012

Acyltransferase

3 of 22

1.65

0.99

0.0089

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF06130

Phosphate propanoyltransferase

3 of 3

2.51

1.97

0.00022

PF00171

Aldehyde dehydrogenase family

3 of 5

2.29

1.85

0.00031

PF17147

Pyruvate:ferredoxin oxidoreductase core domain II

2 of 2

2.51

1.12

0.0090

PF01855

Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg

2 of 2

2.51

1.12

0.0090

PF02775

Thiamine pyrophosphate enzyme, C-terminal TPP binding domain

2 of 5

2.12

0.92

0.0187

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR008300

Phosphate propanoyltransferase

3 of 3

2.51

1.77

0.00052

IPR016163

Aldehyde dehydrogenase, C-terminal

3 of 5

2.29

1.67

0.00072

IPR016161

Aldehyde/histidinol dehydrogenase

3 of 6

2.21

1.65

0.00072

IPR029061

Thiamin diphosphate-binding fold

3 of 10

1.99

1.4

0.0018

IPR033412

Pyruvate:ferredoxin oxidoreductase, core domain II

2 of 2

2.51

1.04

0.0124

(more ...)

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