STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A8273_1288Pyridoxamine 5'-phosphate oxidase-related FMN-binding protein; Scaffold_11_183. (135 aa)    
Predicted Functional Partners:
A8273_966
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; Scaffold_9_14.
     
 0.645
pdxT
Glutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
       0.621
pdxS
Pyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family.
       0.600
A8273_892
Methyl-coenzyme M reductase alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.
 
     0.538
A8273_349
Methanoproteinis marker protein 5; Scaffold_1_92.
  
     0.532
A8273_896
Methyl-coenzyme M reductase beta subunit; Scaffold_6_80.
 
     0.530
A8273_352
Methanoproteinis marker protein 7; Scaffold_1_95.
  
     0.517
A8273_894
Methyl-coenzyme M reductase subunit C; Scaffold_6_78.
 
     0.499
A8273_348
Methanoproteinis marker protein 6; Scaffold_1_91.
  
     0.489
A8273_350
Methanoproteinis marker protein 15; Scaffold_1_93.
 
     0.487
Your Current Organism:
Methanohalophilus sp. 2GBenrich
NCBI taxonomy Id: 1884871
Other names: M. sp. 2-GBenrich, Methanohalophilus sp. 2-GBenrich
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