node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SMG36572.1 | ddl | SAMN03080602_02514 | SAMN03080602_02476 | Aspartate aminotransferase. | D-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.503 |
SMG36572.1 | murB | SAMN03080602_02514 | SAMN03080602_02515 | Aspartate aminotransferase. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.844 |
SMG38901.1 | ddl | SAMN03080602_02794 | SAMN03080602_02476 | UDP-N-acetylmuramate: L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase. | D-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.919 |
SMG38901.1 | murA | SAMN03080602_02794 | SAMN03080602_03546 | UDP-N-acetylmuramate: L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.776 |
SMG38901.1 | murB | SAMN03080602_02794 | SAMN03080602_02515 | UDP-N-acetylmuramate: L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.875 |
SMG38901.1 | murD | SAMN03080602_02794 | SAMN03080602_00292 | UDP-N-acetylmuramate: L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.964 |
SMG38901.1 | murE | SAMN03080602_02794 | SAMN03080602_00290 | UDP-N-acetylmuramate: L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.854 |
SMG38901.1 | murF | SAMN03080602_02794 | SAMN03080602_02831 | UDP-N-acetylmuramate: L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.903 |
SMG38901.1 | murG | SAMN03080602_02794 | SAMN03080602_00294 | UDP-N-acetylmuramate: L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase. | UDP-N-acetylglucosamine-N- acetylmuramylpentapeptide N-acetylglucosamine transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.865 |
ddl | SMG36572.1 | SAMN03080602_02476 | SAMN03080602_02514 | D-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Aspartate aminotransferase. | 0.503 |
ddl | SMG38901.1 | SAMN03080602_02476 | SAMN03080602_02794 | D-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramate: L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase. | 0.919 |
ddl | murA | SAMN03080602_02476 | SAMN03080602_03546 | D-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.765 |
ddl | murB | SAMN03080602_02476 | SAMN03080602_02515 | D-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.829 |
ddl | murC | SAMN03080602_02476 | SAMN03080602_00295 | D-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.994 |
ddl | murD | SAMN03080602_02476 | SAMN03080602_00292 | D-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.947 |
ddl | murE | SAMN03080602_02476 | SAMN03080602_00290 | D-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.879 |
ddl | murF | SAMN03080602_02476 | SAMN03080602_02831 | D-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.995 |
ddl | murG | SAMN03080602_02476 | SAMN03080602_00294 | D-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylglucosamine-N- acetylmuramylpentapeptide N-acetylglucosamine transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.859 |
era | murB | SAMN03080602_03974 | SAMN03080602_02515 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.729 |
murA | SMG38901.1 | SAMN03080602_03546 | SAMN03080602_02794 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | UDP-N-acetylmuramate: L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase. | 0.776 |