DSOL_4394 protein (Desulfosporosinus sp. OL)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

DSOL_4394

Anti-sigma B factor; Belongs to the anti-sigma-factor antagonist family. (114 aa)

Predicted Functional Partners:

spoIIAB

0.998

DSOL_4392

0.968

DSOL_4395

0.873

DSOL_4396

0.857

DSOL_4198

0.853

DSOL_4397

0.833

DSOL_2505

0.824

DSOL_4398

0.816

DSOL_0416

0.793

DSOL_4203

0.793

Your Current Organism:

Desulfosporosinus sp. OL

NCBI taxonomy Id: 1888891
Other names: D. sp. OL

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DSOL_0416	DSOL_2505	DSOL_0416	DSOL_2505	Stage 0 sporulation two-component response regulator (Spo0A); May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.	Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.	0.856
DSOL_0416	DSOL_4198	DSOL_0416	DSOL_4198	Stage 0 sporulation two-component response regulator (Spo0A); May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.	Stage II sporulation serine phosphatase for sigma-F activation (SpoIIE).	0.810
DSOL_0416	DSOL_4203	DSOL_0416	DSOL_4203	Stage 0 sporulation two-component response regulator (Spo0A); May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.	Forespore shell protein.	0.736
DSOL_0416	DSOL_4392	DSOL_0416	DSOL_4392	Stage 0 sporulation two-component response regulator (Spo0A); May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.	RNA polymerase sporulation specific sigma factor SigF; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	0.801
DSOL_0416	DSOL_4394	DSOL_0416	DSOL_4394	Stage 0 sporulation two-component response regulator (Spo0A); May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.	Anti-sigma B factor; Belongs to the anti-sigma-factor antagonist family.	0.793
DSOL_0416	DSOL_4395	DSOL_0416	DSOL_4395	Stage 0 sporulation two-component response regulator (Spo0A); May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.	Stage V sporulation protein AC (SpoVAC).	0.767
DSOL_0416	DSOL_4396	DSOL_0416	DSOL_4396	Stage 0 sporulation two-component response regulator (Spo0A); May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.	Stage V sporulation protein AD (SpoVAD).	0.806
DSOL_0416	DSOL_4397	DSOL_0416	DSOL_4397	Stage 0 sporulation two-component response regulator (Spo0A); May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.	Stage V sporulation protein AE (SpoVAE).	0.752
DSOL_0416	DSOL_4398	DSOL_0416	DSOL_4398	Stage 0 sporulation two-component response regulator (Spo0A); May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.	Stage V sporulation protein AF (SpoVAF).	0.715
DSOL_0416	spoIIAB	DSOL_0416	DSOL_4393	Stage 0 sporulation two-component response regulator (Spo0A); May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.	Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.	0.842
DSOL_2505	DSOL_0416	DSOL_2505	DSOL_0416	Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.	Stage 0 sporulation two-component response regulator (Spo0A); May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.	0.856
DSOL_2505	DSOL_4198	DSOL_2505	DSOL_4198	Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.	Stage II sporulation serine phosphatase for sigma-F activation (SpoIIE).	0.821
DSOL_2505	DSOL_4203	DSOL_2505	DSOL_4203	Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.	Forespore shell protein.	0.793
DSOL_2505	DSOL_4392	DSOL_2505	DSOL_4392	Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.	RNA polymerase sporulation specific sigma factor SigF; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	0.758
DSOL_2505	DSOL_4394	DSOL_2505	DSOL_4394	Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.	Anti-sigma B factor; Belongs to the anti-sigma-factor antagonist family.	0.824
DSOL_2505	DSOL_4395	DSOL_2505	DSOL_4395	Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.	Stage V sporulation protein AC (SpoVAC).	0.805
DSOL_2505	DSOL_4396	DSOL_2505	DSOL_4396	Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.	Stage V sporulation protein AD (SpoVAD).	0.790
DSOL_2505	DSOL_4397	DSOL_2505	DSOL_4397	Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.	Stage V sporulation protein AE (SpoVAE).	0.774
DSOL_2505	DSOL_4398	DSOL_2505	DSOL_4398	Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.	Stage V sporulation protein AF (SpoVAF).	0.771
DSOL_2505	spoIIAB	DSOL_2505	DSOL_4393	Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.	Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.	0.859