STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
secYPreprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (569 aa)    
Predicted Functional Partners:
OIR21058.1
Protein translocase SEC61 complex subunit gamma; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.999
rpl30
50S ribosomal protein L30; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.967
OIR17547.1
30S ribosomal protein S5; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uS5 family.
 
  
 0.947
rpl15
Hypothetical protein; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
 
  
 0.945
OIR17516.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
    0.945
rpl32e
50S ribosomal protein L32e; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL32 family.
 
    0.935
OIR16138.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.888
rpl19e
50S ribosomal protein L19e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family.
 
    0.886
rpl18
50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
 
  
 0.885
adkA
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the archaeal adenylate kinase family.
  
  
 0.865
Your Current Organism:
Marine Group III
NCBI taxonomy Id: 1888995
Other names: M. Group III euryarchaeote CG-Epi1, Marine Group III euryarchaeote CG-Epi1
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