STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANB04341.1SAM-dependent methyltransferase; Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity. (288 aa)    
Predicted Functional Partners:
ANB04345.1
Calcium-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.872
ANB04344.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.805
geoA
Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.770
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
      
 0.673
ANB06649.1
dITP/XTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
      
 0.667
ANB04331.1
LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.663
ANB08791.1
NsdA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.616
ANB04343.1
Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family.
       0.551
srm34
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.502
ANB10181.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.495
Your Current Organism:
Streptomyces ambofaciens
NCBI taxonomy Id: 1889
Other names: ATCC 23877, BCRC 11857, CBS 616.68, CCRC 11857, CCRC:11857, CECT 3101, DSM 40053, IFO 12836, ISP 5053, JCM 4204, JCM 4618, KCTC 9111, NBRC 12836, NRRL 2420, NRRL B-2516, NRRL-ISP 5053, S. ambofaciens
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.