ppnK protein (Streptomyces ambofaciens) - STRING interaction network

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ppnK

NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (354 aa)

Predicted Functional Partners:

nadE

0.944

nadD

0.938

ppnK-2

0.923

nadE-2

0.916

cobB-2

0.915

nudC

0.903

tlyA

0.714

zwf

0.667

zwf-2

0.667

aldH

0.573

Your Current Organism:

Streptomyces ambofaciens

NCBI taxonomy Id: 1889
Other names: ATCC 23877, BCRC 11857, CBS 616.68, CCRC 11857, CCRC:11857, CECT 3101, DSM 40053, IFO 12836, ISP 5053, JCM 4204, JCM 4618, KCTC 9111, NBRC 12836, NRRL 2420, NRRL B-2516, NRRL-ISP 5053, S. ambofaciens

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
aldH	ppnK	SAM40697_1757	SAM40697_0510	Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.573
aldH	ppnK-2	SAM40697_1757	SAM40697_1664	Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.573
cobB-2	nadD	SAM40697_5528	SAM40697_2412	NAD-dependent deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).	0.927
cobB-2	nadE	SAM40697_5528	SAM40697_2126	NAD-dependent deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.	0.943
cobB-2	nadE-2	SAM40697_5528	SAM40697_6337	NAD-dependent deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.	0.916
cobB-2	nudC	SAM40697_5528	SAM40697_4476	NAD-dependent deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	NADH pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.910
cobB-2	ppnK	SAM40697_5528	SAM40697_0510	NAD-dependent deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.915
cobB-2	ppnK-2	SAM40697_5528	SAM40697_1664	NAD-dependent deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.915
nadD	cobB-2	SAM40697_2412	SAM40697_5528	Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).	NAD-dependent deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.927
nadD	nadE	SAM40697_2412	SAM40697_2126	Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).	NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.	0.958
nadD	nadE-2	SAM40697_2412	SAM40697_6337	Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).	NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.	0.961
nadD	nudC	SAM40697_2412	SAM40697_4476	Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).	NADH pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.910
nadD	ppnK	SAM40697_2412	SAM40697_0510	Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).	NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.938
nadD	ppnK-2	SAM40697_2412	SAM40697_1664	Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).	NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.944
nadE	cobB-2	SAM40697_2126	SAM40697_5528	NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.	NAD-dependent deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.943
nadE	nadD	SAM40697_2126	SAM40697_2412	NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.	Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).	0.958
nadE	nadE-2	SAM40697_2126	SAM40697_6337	NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.	NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.	0.910
nadE	nudC	SAM40697_2126	SAM40697_4476	NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.	NADH pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.913
nadE	ppnK	SAM40697_2126	SAM40697_0510	NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.	NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.944
nadE	ppnK-2	SAM40697_2126	SAM40697_1664	NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.	NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.944

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