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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yliKmethylmalonyl-CoA mutase; MDM; functions in conversion of succinate to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology. (725 aa)    
Predicted Functional Partners:
mutA
methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
0.998
ANB08623.1
Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.995
argK
Protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.992
meaA
Protein meaA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
0.989
ANB08621.1
methylmalonyl-CoA epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.982
sucD
succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
    
 0.943
korA
2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.937
sucC
succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.932
ANB10370.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.912
ANB06260.1
acyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.908
Your Current Organism:
Streptomyces ambofaciens
NCBI taxonomy Id: 1889
Other names: ATCC 23877, BCRC 11857, CBS 616.68, CCRC 11857, CCRC:11857, CECT 3101, DSM 40053, IFO 12836, ISP 5053, JCM 4204, JCM 4618, KCTC 9111, NBRC 12836, NRRL 2420, NRRL B-2516, NRRL-ISP 5053, S. ambofaciens
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.