Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cobHprecorrin-8X methylmutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (198 aa)    
Predicted Functional Partners:
ANB05700.1
precorrin-6Y C5,15-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.999
ANB05701.1
Precorrin methylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.999
ANB05394.1
Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.998
cobB
Cobyrinic acid ac-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
 
 0.997
cbiF
Precorrin-4 C11-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.996
cbiX
Cobalamin biosynthesis protein CbiX; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.995
cobQ
Cobalamin biosynthesis protein CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
  
 0.993
ANB05697.1
Precorrin-2 C20-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family.
 
  
 0.983
cobK
cobalt-precorrin-6X reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.970
ANB05704.1
Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.954
Your Current Organism:
Streptomyces ambofaciens
NCBI taxonomy Id: 1889
Other names: ATCC 23877, BCRC 11857, CBS 616.68, CCRC 11857, CCRC:11857, CECT 3101, DSM 40053, IFO 12836, ISP 5053, JCM 4204, JCM 4618, KCTC 9111, NBRC 12836, NRRL 2420, NRRL B-2516, NRRL-ISP 5053, S. ambofaciens
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