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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANB05821.1Sugar kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (309 aa)    
Predicted Functional Partners:
psuG
Pseudouridine-5-phosphate glycosidase; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family.
 
  
 0.934
ANB05819.1
Dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.787
rbsD
Ribose ABC transporter; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
 
  
 0.777
ANB09790.1
5-deoxy-glucuronate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.647
priA-2
1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Involved in both the histidine and tryptophan biosynthetic pathways; Belongs to the HisA/HisF family.
  
  
 0.629
iolD
3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (decyclizing); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family.
  
  
 0.588
ANB05818.1
Cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
     
 0.575
rihA
Nucleoside hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.518
ANB06919.1
PTS lactose transporter subunit IIC; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.490
ANB05817.1
Glycerophosphodiester phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.446
Your Current Organism:
Streptomyces ambofaciens
NCBI taxonomy Id: 1889
Other names: ATCC 23877, BCRC 11857, CBS 616.68, CCRC 11857, CCRC:11857, CECT 3101, DSM 40053, IFO 12836, ISP 5053, JCM 4204, JCM 4618, KCTC 9111, NBRC 12836, NRRL 2420, NRRL B-2516, NRRL-ISP 5053, S. ambofaciens
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