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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANB05928.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (365 aa)    
Predicted Functional Partners:
ANB05927.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.826
lspA
Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
     
 0.609
ANB05926.1
RNA pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
  
    0.578
ANB05925.1
Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.576
ANB04801.1
Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.489
ANB05930.1
DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.460
lexA
LexA family transcriptional regulator; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
     
 0.458
recA
DNA recombination/repair protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
     
 0.453
ANB06171.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.434
ANB06263.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.428
Your Current Organism:
Streptomyces ambofaciens
NCBI taxonomy Id: 1889
Other names: ATCC 23877, BCRC 11857, CBS 616.68, CCRC 11857, CCRC:11857, CECT 3101, DSM 40053, IFO 12836, ISP 5053, JCM 4204, JCM 4618, KCTC 9111, NBRC 12836, NRRL 2420, NRRL B-2516, NRRL-ISP 5053, S. ambofaciens
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.