Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
bfrBacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family. (167 aa)    
Predicted Functional Partners:
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
     
 0.921
ANB05972.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.901
hmuO
Heme oxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.900
yuiH
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.759
ideR
Dihydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.674
ANB04411.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.622
ANB04437.1
Protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.599
ANB06627.1
Regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.586
ANB04693.1
PAS sensor protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.582
ANB08899.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.580
Your Current Organism:
Streptomyces ambofaciens
NCBI taxonomy Id: 1889
Other names: ATCC 23877, BCRC 11857, CBS 616.68, CCRC 11857, CCRC:11857, CECT 3101, DSM 40053, IFO 12836, ISP 5053, JCM 4204, JCM 4618, KCTC 9111, NBRC 12836, NRRL 2420, NRRL B-2516, NRRL-ISP 5053, S. ambofaciens
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