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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
actIIHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (680 aa)    
Predicted Functional Partners:
ecrA
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.840
yxjL-6
LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.835
srm10
Polyketide synthase subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.682
dasR
GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.651
afsR-2
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.650
cya
Adenylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.515
crp
Crp/Fnr family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.511
frr
Ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.
      
 0.491
rpsL
30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
      
 0.441
ANB06320.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.437
Your Current Organism:
Streptomyces ambofaciens
NCBI taxonomy Id: 1889
Other names: ATCC 23877, BCRC 11857, CBS 616.68, CCRC 11857, CCRC:11857, CECT 3101, DSM 40053, IFO 12836, ISP 5053, JCM 4204, JCM 4618, KCTC 9111, NBRC 12836, NRRL 2420, NRRL B-2516, NRRL-ISP 5053, S. ambofaciens
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