| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ANB05506.1 | ANB07768.1 | SAM40697_1546 | SAM40697_3810 | Luciferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cation-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.648 |
| ANB05506.1 | cofC | SAM40697_1546 | SAM40697_4808 | Luciferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-phospho-L-lactate guanylyltransferase; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor. | 0.562 |
| ANB05506.1 | cofD | SAM40697_1546 | SAM40697_2812 | Luciferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-phospho-L-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP. | 0.771 |
| ANB05506.1 | fbiB | SAM40697_1546 | SAM40697_2813 | Luciferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | F420-0--gamma-glutamyl ligase; Bifunctional enzyme that catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives, and the FMNH2- dependent reduction of dehydro-F420-0 to form F420-0. | 0.743 |
| ANB05798.1 | cofD | SAM40697_1838 | SAM40697_2812 | glmZ(sRNA)-inactivating NTPase; Displays ATPase and GTPase activities. | 2-phospho-L-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP. | 0.854 |
| ANB05798.1 | whiA | SAM40697_1838 | SAM40697_1836 | glmZ(sRNA)-inactivating NTPase; Displays ATPase and GTPase activities. | Sporulation protein; Involved in cell division and chromosome segregation. | 0.946 |
| ANB06649.1 | cofD | SAM40697_2690 | SAM40697_2812 | dITP/XTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 2-phospho-L-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP. | 0.849 |
| ANB06649.1 | whiA | SAM40697_2690 | SAM40697_1836 | dITP/XTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Sporulation protein; Involved in cell division and chromosome segregation. | 0.716 |
| ANB06769.1 | ANB06772.1 | SAM40697_2811 | SAM40697_2814 | Cysteine dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-methyladenine DNA glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.757 |
| ANB06769.1 | cofD | SAM40697_2811 | SAM40697_2812 | Cysteine dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-phospho-L-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP. | 0.835 |
| ANB06769.1 | fbiB | SAM40697_2811 | SAM40697_2813 | Cysteine dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | F420-0--gamma-glutamyl ligase; Bifunctional enzyme that catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives, and the FMNH2- dependent reduction of dehydro-F420-0 to form F420-0. | 0.835 |
| ANB06772.1 | ANB06769.1 | SAM40697_2814 | SAM40697_2811 | 3-methyladenine DNA glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cysteine dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.757 |
| ANB06772.1 | cofD | SAM40697_2814 | SAM40697_2812 | 3-methyladenine DNA glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-phospho-L-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP. | 0.831 |
| ANB06772.1 | fbiB | SAM40697_2814 | SAM40697_2813 | 3-methyladenine DNA glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | F420-0--gamma-glutamyl ligase; Bifunctional enzyme that catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives, and the FMNH2- dependent reduction of dehydro-F420-0 to form F420-0. | 0.789 |
| ANB07768.1 | ANB05506.1 | SAM40697_3810 | SAM40697_1546 | Cation-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Luciferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.648 |
| ANB07768.1 | cofC | SAM40697_3810 | SAM40697_4808 | Cation-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-phospho-L-lactate guanylyltransferase; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor. | 0.624 |
| ANB07768.1 | cofD | SAM40697_3810 | SAM40697_2812 | Cation-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-phospho-L-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP. | 0.787 |
| ANB07768.1 | fbiB | SAM40697_3810 | SAM40697_2813 | Cation-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | F420-0--gamma-glutamyl ligase; Bifunctional enzyme that catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives, and the FMNH2- dependent reduction of dehydro-F420-0 to form F420-0. | 0.808 |
| ANB07768.1 | fbiC | SAM40697_3810 | SAM40697_3004 | Cation-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-phospho-L-lactate guanylyltransferase; 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase; catalyzes radical-mediated transfer of hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO); functions in F420 biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.588 |
| cofC | ANB05506.1 | SAM40697_4808 | SAM40697_1546 | 2-phospho-L-lactate guanylyltransferase; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor. | Luciferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.562 |
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