Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ANB07231.1ArsR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (167 aa)    
Predicted Functional Partners:
ANB07230.1
Peptidase M23; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.863
ANB07228.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.761
ANB07232.1
Phosphoribosylglycinamide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.738
ANB07233.1
Phosphoribosylformylglycinamidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.738
purS
Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...]
       0.738
ANB07227.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.716
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
       0.670
lsr
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.638
purM
Phosphoribosylaminoimidazole synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.573
ANB09680.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.570
Your Current Organism:
Streptomyces ambofaciens
NCBI taxonomy Id: 1889
Other names: ATCC 23877, BCRC 11857, CBS 616.68, CCRC 11857, CCRC:11857, CECT 3101, DSM 40053, IFO 12836, ISP 5053, JCM 4204, JCM 4618, KCTC 9111, NBRC 12836, NRRL 2420, NRRL B-2516, NRRL-ISP 5053, S. ambofaciens
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