Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ANB07254.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (98 aa)    
Predicted Functional Partners:
ANB07538.1
Twitching motility protein PilT; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.768
ANB07255.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.747
ANB08598.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.706
disA
DNA integrity scanning protein DisA; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
  
     0.651
ANB08705.1
Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.619
ANB08139.1
Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.566
ANB08871.1
GCN5 family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.547
ANB07251.1
Fe-S cluster assembly protein HesB; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.544
ANB07408.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.507
ANB06765.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.503
Your Current Organism:
Streptomyces ambofaciens
NCBI taxonomy Id: 1889
Other names: ATCC 23877, BCRC 11857, CBS 616.68, CCRC 11857, CCRC:11857, CECT 3101, DSM 40053, IFO 12836, ISP 5053, JCM 4204, JCM 4618, KCTC 9111, NBRC 12836, NRRL 2420, NRRL B-2516, NRRL-ISP 5053, S. ambofaciens
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