| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ANB05791.1 | ANB06621.1 | SAM40697_1831 | SAM40697_2662 | Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.985 |
| ANB05791.1 | ffh | SAM40697_1831 | SAM40697_4838 | Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Signal recognition particle; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.975 |
| ANB05791.1 | ftsY | SAM40697_1831 | SAM40697_4832 | Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.989 |
| ANB05791.1 | secA | SAM40697_1831 | SAM40697_2782 | Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.998 |
| ANB05791.1 | secE | SAM40697_1831 | SAM40697_4017 | Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.999 |
| ANB05791.1 | secF-2 | SAM40697_1831 | SAM40697_5370 | Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.999 |
| ANB05791.1 | secY | SAM40697_1831 | SAM40697_4067 | Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.999 |
| ANB05791.1 | yidC | SAM40697_1831 | SAM40697_3424 | Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase YidC; Functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.985 |
| ANB06621.1 | ANB05791.1 | SAM40697_2662 | SAM40697_1831 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.985 |
| ANB06621.1 | ANB07383.1 | SAM40697_2662 | SAM40697_3425 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Membrane protein insertion efficiency factor YidD; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | 0.888 |
| ANB06621.1 | ffh | SAM40697_2662 | SAM40697_4838 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Signal recognition particle; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.947 |
| ANB06621.1 | ftsY | SAM40697_2662 | SAM40697_4832 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.944 |
| ANB06621.1 | jag | SAM40697_2662 | SAM40697_3423 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Single-stranded DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.808 |
| ANB06621.1 | secA | SAM40697_2662 | SAM40697_2782 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.961 |
| ANB06621.1 | secE | SAM40697_2662 | SAM40697_4017 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Preprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.969 |
| ANB06621.1 | secF-2 | SAM40697_2662 | SAM40697_5370 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Preprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.999 |
| ANB06621.1 | secY | SAM40697_2662 | SAM40697_4067 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.993 |
| ANB06621.1 | yidC | SAM40697_2662 | SAM40697_3424 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Preprotein translocase YidC; Functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.923 |
| ANB07383.1 | ANB06621.1 | SAM40697_3425 | SAM40697_2662 | Membrane protein insertion efficiency factor YidD; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.888 |
| ANB07383.1 | jag | SAM40697_3425 | SAM40697_3423 | Membrane protein insertion efficiency factor YidD; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | Single-stranded DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.962 |
STRING v12.5 is now available!
