STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEK29636.1Nitrogen regulatory protein P-II family; Belongs to the P(II) protein family. (118 aa)    
Predicted Functional Partners:
SEK29587.1
Ammonium transporter.
 0.999
SEK89078.1
Two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL.
  
 0.983
argB
N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
    
 
 0.955
glnD
UTP--GlnB (protein PII) uridylyltransferase, GlnD; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
 
 
 0.953
SEK25544.1
Hypothetical protein.
    
 
 0.861
SEK57372.1
Hypothetical protein.
    
 
 0.861
SEL15164.1
Tetratricopeptide repeat-containing protein.
    
 
 0.861
SEL53400.1
Flp pilus assembly protein TadD, contains TPR repeats.
    
 
 0.861
SEK39957.1
Glutamate synthase (NADPH) large subunit.
     
 0.753
nadE
NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
     
 0.517
Your Current Organism:
Jannaschia helgolandensis
NCBI taxonomy Id: 188906
Other names: DSM 14858, J. helgolandensis, Jannaschia helgolandensis Wagner-Dobler et al. 2003, NCIMB 13941, strain Hel 10
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.