node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SEK65025.1 | SEK65057.1 | SAMN04488526_1149 | SAMN04488526_1150 | precorrin-8X methylmutase. | precorrin-6Y C5,15-methyltransferase (decarboxylating). | 0.999 |
SEK65025.1 | SEK65097.1 | SAMN04488526_1149 | SAMN04488526_1151 | precorrin-8X methylmutase. | Precorrin-2/cobalt-factor-2 C20-methyltransferase. | 0.997 |
SEK65025.1 | SEK65126.1 | SAMN04488526_1149 | SAMN04488526_1152 | precorrin-8X methylmutase. | Cobalt-precorrin 5A hydrolase / precorrin-3B C17-methyltransferase. | 0.999 |
SEK65025.1 | SEK65165.1 | SAMN04488526_1149 | SAMN04488526_1153 | precorrin-8X methylmutase. | Precorrin-4/cobalt-precorrin-4 C11-methyltransferase. | 0.997 |
SEK65025.1 | SEK91478.1 | SAMN04488526_1149 | SAMN04488526_1542 | precorrin-8X methylmutase. | precorrin-6A/cobalt-precorrin-6A reductase. | 0.990 |
SEK65025.1 | SEL10449.1 | SAMN04488526_1149 | SAMN04488526_1933 | precorrin-8X methylmutase. | uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.625 |
SEK65025.1 | cbiD | SAMN04488526_1149 | SAMN04488526_1543 | precorrin-8X methylmutase. | cobalt-precorrin-5B (C1)-methyltransferase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | 0.979 |
SEK65025.1 | cobB-2 | SAMN04488526_1149 | SAMN04488526_1545 | precorrin-8X methylmutase. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.995 |
SEK65025.1 | cobQ | SAMN04488526_1149 | SAMN04488526_2874 | precorrin-8X methylmutase. | Adenosylcobyric acid synthase (glutamine-hydrolysing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.989 |
SEK65057.1 | SEK65025.1 | SAMN04488526_1150 | SAMN04488526_1149 | precorrin-6Y C5,15-methyltransferase (decarboxylating). | precorrin-8X methylmutase. | 0.999 |
SEK65057.1 | SEK65097.1 | SAMN04488526_1150 | SAMN04488526_1151 | precorrin-6Y C5,15-methyltransferase (decarboxylating). | Precorrin-2/cobalt-factor-2 C20-methyltransferase. | 0.998 |
SEK65057.1 | SEK65126.1 | SAMN04488526_1150 | SAMN04488526_1152 | precorrin-6Y C5,15-methyltransferase (decarboxylating). | Cobalt-precorrin 5A hydrolase / precorrin-3B C17-methyltransferase. | 0.999 |
SEK65057.1 | SEK65165.1 | SAMN04488526_1150 | SAMN04488526_1153 | precorrin-6Y C5,15-methyltransferase (decarboxylating). | Precorrin-4/cobalt-precorrin-4 C11-methyltransferase. | 0.999 |
SEK65057.1 | SEK91478.1 | SAMN04488526_1150 | SAMN04488526_1542 | precorrin-6Y C5,15-methyltransferase (decarboxylating). | precorrin-6A/cobalt-precorrin-6A reductase. | 0.994 |
SEK65057.1 | SEL10449.1 | SAMN04488526_1150 | SAMN04488526_1933 | precorrin-6Y C5,15-methyltransferase (decarboxylating). | uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.941 |
SEK65057.1 | cbiD | SAMN04488526_1150 | SAMN04488526_1543 | precorrin-6Y C5,15-methyltransferase (decarboxylating). | cobalt-precorrin-5B (C1)-methyltransferase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | 0.998 |
SEK65057.1 | cobB-2 | SAMN04488526_1150 | SAMN04488526_1545 | precorrin-6Y C5,15-methyltransferase (decarboxylating). | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.928 |
SEK65057.1 | cobQ | SAMN04488526_1150 | SAMN04488526_2874 | precorrin-6Y C5,15-methyltransferase (decarboxylating). | Adenosylcobyric acid synthase (glutamine-hydrolysing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.880 |
SEK65097.1 | SEK65025.1 | SAMN04488526_1151 | SAMN04488526_1149 | Precorrin-2/cobalt-factor-2 C20-methyltransferase. | precorrin-8X methylmutase. | 0.997 |
SEK65097.1 | SEK65057.1 | SAMN04488526_1151 | SAMN04488526_1150 | Precorrin-2/cobalt-factor-2 C20-methyltransferase. | precorrin-6Y C5,15-methyltransferase (decarboxylating). | 0.998 |