STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEK95872.12-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). (282 aa)    
Predicted Functional Partners:
SEK95846.1
Lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
  0.882
SEK95967.1
2-keto-3-deoxy-L-fuconate dehydrogenase.
  0.817
SEL64751.1
Fumarylpyruvate hydrolase.
  
  
 
0.779
glcB
Malate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
    
 0.740
SEL52630.1
Glycolate oxidase iron-sulfur subunit.
  
 
  0.729
SEL56094.1
Glyoxylate/hydroxypyruvate reductase A.
    
  0.722
SEK39228.1
Homogentisate 1,2-dioxygenase.
  
  
 0.695
SEK95908.1
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
       0.661
SEK57259.1
Succinate dehydrogenase subunit A; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
  
 
  0.598
fumC
Fumarase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
   
 0.581
Your Current Organism:
Jannaschia helgolandensis
NCBI taxonomy Id: 188906
Other names: DSM 14858, J. helgolandensis, Jannaschia helgolandensis Wagner-Dobler et al. 2003, NCIMB 13941, strain Hel 10
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.