STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
rbsK6-phosphofructokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (311 aa)    
Predicted Functional Partners:
SEK91063.1
Purine nucleosidase.
 
 0.916
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
   
 0.853
rpiA
Ribose-5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
   
 0.849
SEL69954.1
L-fucose mutarotase; Belongs to the RbsD / FucU family.
 
     0.831
SEL25901.1
Transketolase; Belongs to the transketolase family.
   
 0.828
SEK25888.1
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate.
    
 0.798
SEL69982.1
Lysophospholipase L1.
    
  0.796
SEL17882.1
Phosphomannomutase / phosphoglucomutase.
   
 
 0.785
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.765
SEL70040.1
Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.
       0.693
Your Current Organism:
Jannaschia helgolandensis
NCBI taxonomy Id: 188906
Other names: DSM 14858, J. helgolandensis, Jannaschia helgolandensis Wagner-Dobler et al. 2003, NCIMB 13941, strain Hel 10
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